Shared topics

Endocrine

Hyperglycemia without ketoacidosis

Tell marked hyperglycemia without ketoacidosis apart from diabetic ketoacidosis.

Educational only. A local note appears only when a public source is attached. This page does not say that one exam, or training in one country, makes you eligible to practice in another.

Global core

Marked hyperglycemia with dehydration can be dangerous without ketoacidosis. Ketones and acidosis are what make a diabetic-ketoacidosis protocol the right one. A person who is alert, not vomiting, and ketone-negative still needs assessment the same day. Which glucose-lowering drug is first, and which HbA1c or glucose target is published, are local and are not stated here as one worldwide rule.

What stays the same

  • Ketones and acidosis decide whether a ketoacidosis protocol applies.
  • A walking patient with a high glucose still needs a same-day plan.
  • The first drug and the numeric target are local.
  1. Recognize. Thirst, polyuria, weight loss, or a glucose that is far above the usual range.
  2. Reason. Ketones, pH, and how dry the patient is separate ketoacidosis, a hyperosmolar state, and stable hyperglycemia.
  3. Prioritize. Shock, a falling consciousness, and a very high osmolality come first.
  4. Act safely. If this is not ketoacidosis, do not copy that protocol. Assess, replace fluid if he is dry, and start a plan. Look up the local first drug.

Local adaptation

No sourced local note is attached to this topic. That is not a statement that every country manages it the same way. The shared principle above is what this beta is willing to teach.

Exam lens

The next step in a very high glucose: which protocol applies, and who cannot go home.

Original case · shared decision

The lens above is how that exam usually frames the medicine. This case stays on the shared decision. Not an official examination item.

A 62-year-old man has thirst and polyuria. A finger-stick glucose is 22 mmol/L (about 396 mg/dL). He is alert, not vomiting, and not breathless. Urine ketones are negative and a venous pH is 7.38. What is the most appropriate framing?